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Department of Quantitative Biomedicine

The Polymenidou group publishes their collaborative work on direct binding of importins to arginine-rich dipeptide repeat proteins

Nuclear Import Receptors Directly Bind to Arginine-Rich Dipeptide Repeat Proteins and Suppress Their Pathological Interactions

This work results from a collaboration between the groups of Magdalini Polymenidou and J. Shorter (Perelman School of Medicine, University of Pennsylvania, Philadelphia USA), D. Edbauer (German Center for Neurodegenerative Diseases (DZNE), Munich, Germany), T. Madl (Medical University of Graz, Austria) and D. Dormann (Ludwig-Maximilians-University Munich, Germany).

See Hutten et al, Cell Reports

Fig.1 Hutten et al. © 2020 The Authors