The Bodenmiller group publishes their work on spatial phenotypic variability in 3D spheroids
A quantitative analysis of the interplay of environment, neighborhood, and cell state in 3D spheroids
In this work, the Bodenmiller group developed a novel barcoding approach that enables high throughput multiplexed imaging of 3D microtissues using Imaging Mass Cytometry.
See Zanotelli et al., Mol Syst Biol.