Sharing is caring: The benefits of distributing protein aggregates among microglial networks
Trafficking of protein aggregates through neural networks is known to cause propagation of pathology and toxicity in neurodegenerative diseases. Scheiblich et al. (2021) describe an advantageous aggregate-sharing strategy, challenging the view that pathological protein propagation only has a detrimental outcome on network longevity.
Spotlight article: Wiersma and Polymenidou, Neuron
Original publication: Scheiblling et al, Cell