Publications

The co-inhibitory receptor TIGIT promotes tissue-protective functions in T cells

CD4 T Cells Acquire Innate Capability Upon Classical T Cell Activation

Chronic antigen stimulation in melanoma induces T cell exhaustion and limits efficacy of T cell bispecific therapies

Clonally expanded IgG, but not IgA, antibody-secreting cells preferentially target influenza nucleoprotein following homologous and heterologous infections

Immune Checkpoint Agonists for Inflammatory Skin Diseases

TIGIT predominantly regulates the immune response via regulatory T cells

Innate acting memory Th1 cells modulate heterologous diseases

TIGIT acts as an immune checkpoint upon inhibition of PD1 signaling in autoimmune diabetes

LAG-3, TIM-3, and TIGIT: Distinct functions in immune regulation

Ovarian cancer G protein-coupled receptor 1 deficiency exacerbates crystal deposition and kidney injury in oxalate nephropathy in female mice

Treg-selective IL-2 starvation synergizes with CD40 activation to sustain durable responses in lymphoma models

Single-cell immune repertoire sequencing of B and T cells in murine models of infection and autoimmunity

Nematode microRNAs can Individually Regulate Interferon Regulatory Factor 4 and mTOR in Differentiating T Helper 2 Lymphocytes and Modulate Cytokine Production in Macrophages

Moving to the Outskirts: Interplay Between Regulatory T Cells and Peripheral Tissues

Alkali therapy protects renal function, suppresses inflammation, and improves cellular metabolism in kidney disease

Asymmetric cell division shapes naive and virtual memory T-cell immunity during ageing

Dampening antiviral immunity can protect the host

CD85k Contributes to Regulatory T Cell Function in Chronic Viral Infections

Checkpoint Receptor TIGIT Expressed on Tim-1⁺ B Cells Regulates Tissue Inflammation

Type 1 T_reg cells act as unexpected helpers

Preceding Viral Infections Do Not Imprint Long-Term Changes in Regulatory T Cell Function

Rapid expansion of Treg cells protects from collateral colitis following a viral trigger

Chronic viral infections impinge on naive bystander CD8 T cells

TIGIT limits immune pathology during viral infections

Role of Co-stimulatory Molecules in T Helper Cell Differentiation

Infection History Determines Susceptibility to Unrelated Diseases

Persistence of Candida albicans in the Oral Mucosa Induces a Curbed Inflammatory Host Response That Is Independent of Immunosuppression

The Skin Commensal Yeast Malassezia Triggers a Type 17 Response that Coordinates Anti-fungal Immunity and Exacerbates Skin Inflammation

Chronic virus infection compromises memory bystander T cell function in an IL-6/STAT1-dependent manner

Common Features of Regulatory T Cell Specialization During Th1 Responses

Langerin+ DCs regulate innate IL-17 production in the oral mucosa during Candida albicans-mediated infection

Functional Anti-TIGIT Antibodies Regulate Development of Autoimmunity and Antitumor Immunity

Mechanistic Differences in Neuropathic Pain Modalities Revealed by Correlating Behavior with Global Expression Profiling

Tim-3, Lag-3, and TIGIT

Protein C receptor (PROCR) is a negative regulator of Th17 pathogenicity

Regulatory T cells: balancing protection versus pathology

Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation

CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity

TIGIT predominantly regulates the immune response via regulatory T cells

MicroRNA-21 promotes Th17 differentiation and mediates experimental autoimmune encephalomyelitis

Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses

Good guys gone bad: exTreg cells promote autoimmune arthritis

The CD226/CD155 interaction regulates the proinflammatory (Th1/Th17)/anti-inflammatory (Th2) balance in humans

IL-21 promotes CD8+ CTL activity via the transcription factor T-bet

Assessment of legionella-specific immunity in mice

IFN-γ limits Th9-mediated autoimmune inflammation through dendritic cell modulation of IL-27

Immune checkpoints in central nervous system autoimmunity

Identification of protective B cell antigens of Legionella pneumophila

Type-I IFN drives the differentiation of short-lived effector CD8+ T cells in vivo

Silencing microRNA-155 ameliorates experimental autoimmune encephalomyelitis

Antibody-Fc receptor interactions in protection against intracellular pathogens

Cutting edge: TIGIT has T cell-intrinsic inhibitory functions

Antibodies protect against intracellular bacteria by Fc receptor-mediated lysosomal targeting

Th cells act via two synergistic pathways to promote antiviral CD8+ T cell responses

The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27

A novel role for neutrophils as critical activators of NK cells

Induction and protective role of antibodies in Legionella pneumophila infection

MyD88-dependent IFN-gamma production by NK cells is key for control of Legionella pneumophila infection