Our understanding of host-pathogen interaction is primarily derived from studying how the immune system protects us from a single pathogen. In contrast, it is largely unknown how this response alters the body’s ability to respond to a second infectious agent or the susceptibility to autoimmunity or cancer. Our goal is to investigate the long-term effects of pathogenic challenges on future responses. Currently, we are focusing on changes in the regulatory compartment of the adaptive immune system.
Specifically we aim to:
To achieve this goal we use a wide variety of techniques including:
transcriptomics, high dimensional flow cytometry, in vitro and in vivo immunological assays, animal models (infectious and autoimmune).
|Professor for Immunology, DQBM, UZH, Switzerland
|SNSF/ERC Assistant Professor, Institute for Experimental Immunology, UZH, Switzerland
|Postdoctoral Research Fellow, Harvard Medical School; Brigham & Women's Hospital; Broad Institute of MIT and Harvard; Boston, USA
Prof. Dr. Vijay Kuchroo
|PhD in Immunology, ETH Zurich, Switzerland
Prof. Dr. Annette Oxenius
|Diploma in Natural Sciences (Biochemistry), ETH Zurich, Switzerland