A study co-authored by Rolf Kümmerli from the Kümmerli Lab at the Department of Quantitative Biomedicine provides a comprehensive overview of antibiotic resistance patterns across Ghana. Published in Frontiers in Microbiology, the narrative review analyzes regional variations in resistance among ESKAPEE pathogens using data from human, animal, and environmental sources.
The authors report widespread multidrug resistance across all studied regions, alongside pronounced geographic imbalances in surveillance and research coverage. Critical resistance mechanisms, including carbapenemase and colistin resistance genes, were detected, underscoring the need for targeted interventions.
The findings emphasize that antibiotic resistance in Ghana follows a patterned, region-specific landscape and call for strengthened, standardized surveillance within a One Health framework to support effective national policy implementation.
DOI: https://doi.org/10.3389/fmicb.2025.1696696