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Strain Identity Crucial for Bacterial Community Functioning

New research published in The ISME Journal, involving the Kümmerli Lab at DQBM, demonstrates that individual bacterial strain identities contribute more significantly to community functioning than previously assumed strain interactions.

Using 64 strains of Pseudomonas bacteria isolated from diverse environmental settings, the researchers assessed the importance of strain identities and their interactions in determining two critical microbial functions: overall productivity and iron-scavenging siderophore production. Combining experimental and computational approaches, they found that while strain interactions—especially through secreted molecules like siderophores—were impactful, the individual characteristics of each strain predominantly dictated community behavior and productivity.

This result emphasizes that microbiome engineering strategies aimed at enhancing beneficial microbial interactions must account for inherent differences among bacterial strains. The research highlights a nuanced understanding of bacterial communities, informing approaches in biotechnology, environmental management, and human health.

 

Strain types differ in their growth and pyoverdine production profiles. (A) Growth and (B) pyoverdine production of PVDPRO, PVD, NONPRO, and NON strains isolated from eight soil (empty small circles) and eight freshwater (filled small circles) communities (one strain per type and community), measured under iron-limited and iron-rich conditions. Small circles represent the median of four replicates obtained for each strain under each condition. Large circles and black lines show mean and confidence interval, respectively. Letters show significantly different types in each iron conditions. All types grew more and, with the exception of NON strains, produced less pyoverdine under iron-rich as compared to iron-limited conditions

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