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Department of Quantitative Biomedicine

Bernd Bodenmiller

Please visit the lab website and follow us on twitter

Single cell systems biology of cancer

Our lab develops experimental and computational methods to unravel regulatory systems on the single-cell level that underlie cancer development. Tumors are a tissue disease: A tumor is an assembly of a myriad of cancer cell clones and their differentiation continua and also includes different types of normal cells. The regulatory circuits of each of these cells are coupled to inter-cellular regulatory systems that rely on cell-to-cell communication and spatial features. The intricate interplay of these coupled control systems has a strong influence on tumor development and ultimately disease progression. Our group’s goal is to develop methods based on CyTOF mass cytometry to quantitatively analyze trans-cellular circuits. Based on the mass cytometry data we model and analyze how complex cell phenotypes in tumors are controlled. Our hope is that this will enable targeted modulation that interferes with the hallmarks of cancer and tumor development.

Tags: Imaging mass cytometry, CyTOF, network analysis, systems biology of cancer, tumor biology.

Short CV Prof. Dr. Bernd Bodenmiller


1999-2001:     Vordiplom (Biochemistry), University of Bayreuth
2001-2004:   Diplom (Biochemistry), ETH Zurich
2004-2008:   Ph.D. Systems Biology (ETH Zurich, Lab of Ruedi Aebersold)
2008-2009:   Postdoc (ETH Zurich, Lab of Ruedi Aebersold)
2009-2012:   Postdoc (Stanford University, Lab of Garry P. Nolan)
2013-2019   SNSF Assistant Professor, IMLS, University of Zurich (UZH)
since 2019   Director, Department of Quantitative Biomedicine (DQBM), UZH 
October 2020
  Dual Professorship for Quantitative Biomedicine,
DQBM, UZH & ETH Zurich

These funding agencies support the Bodenmiller group:

BB funding Feb 2021

Weiterführende Informationen


Prof. Dr. Bernd Bodenmiller Professor for Quantitative Biomedicine

Department of Quantitative Biomedicine
University of Zurich
Winterthurerstrasse 190
CH-8057 Zurich

Building / Room: Y38-M-08
phone: +41 44 635 31 28
fax: +41 44 635 68 79


Administrative Assistant:
Franziska Heinzel
Building/Room: Y38-M-02
phone: +41 44 635 48 25

Video Comprehensive Cancer Center Zurich

Forschung am Comprehensive Cancer Center Zurich (CCCZ)

More about Forschung am Comprehensive Cancer Center Zurich (CCCZ)

In diesem Video erklärt Bernd Bodenmiller, wie die innovative Krebsforschung am CCCZ Krebspatientinnen und -patienten Zugang zu personalisierten Behandlungskonzepten ermöglicht.

Strategy& Insider podcast

Strategy& Insider podcast with Bernd Bodenmiller

Listen to the Strategy& Insider podcast Episode 15 with Bernd Bodenmiller: "Transforming the way we deal with cancer".

Listen via Apple Podcast

Listen via Spotify

Bernd Bodenmiller

"Bridging the Gap to Patients"

On the occasion of the 2021 DQBM Founding Symposium, UZH News interviewed DQBM's Founding Director Prof. Bernd Bodenmiller. Please find the article  here.


Bernd Bodenmiller receives highest Swiss biochemistry prize

Bernd Bodenmiller was awarded the prestigious Friedrich Miescher Prize in 2019 for his work at the Institute of Molecular Biology at the University of Zurich. The prize goes to young scientists who have already made a significant contribution to biochemical research in Switzerland.


UZH Magazin zu Präzisionsmedizin

Wie Krebszellen kommunizieren
Bernd Bodenmillers Forschung ermöglicht differenzierte Einblicke in Tumoren. Der Quantitative Biologe zeigt, wie unterschiedliche Zellen in krankem Gewebe zusammenspielen, und bereitet damit den Weg für gezieltere Eingriffe.

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