<url>https://www.dqbm.uzh.ch:443/dam/jcr:fde58e54-da20-48ef-bb73-bdebb4d0c659/News_1024_342-1.png</url> </image> <item> <title>Vision-Language Models Miss Lung Nodules</h1> <article> <h1>Vision-Language Models Miss Lung Nodules</h1> <p>Tue, 04 Aug 2026 22:00:00 GMT</p> <p>A study involving the DQBM Krauthammer Lab evaluates six vision-language models for detecting lung nodules on chest radiographs. All models showed low sensitivity in a zero-shot setting, highlighting important limitations for clinical use.</p> </article> <article> <h1>Machine Learning Targets MRI Appointment No-Shows</h1> <p>Mon, 03 Aug 2026 22:00:00 GMT</p> <p>A study from the DQBM Krauthammer Lab evaluates machine learning for predicting MRI appointment no-shows and tests a targeted reminder intervention in clinical practice. The results highlight both the potential and the challenges of translating predictive models into effective hospital workflows.</p> </article> <article> <h1>Rapid Protocol Generates Functional Human Astrocytes</h1> <p>Tue, 14 Jul 2026 22:00:00 GMT</p> <p>An international study involving the DQBM Polymenidou Lab introduces a simple one-step method to generate functional human astrocytes from induced pluripotent stem cells. The protocol enables robust human astrocyte-neuron co-cultures for studying neural development and disease.</p> </article> <article> <h1>Multi-Omics Profiling Guides Ovarian Cancer Treatment</h1> <p>Sun, 12 Jul 2026 22:00:00 GMT</p> <p>A <em>Nature Communications</em> study involving the DQBM Bodenmiller Lab shows how comprehensive multi-omics profiling can inform personalized treatment strategies for high-grade serous ovarian cancer. The study also reveals how chemotherapy reshapes tumor heterogeneity and genomic instability.</p> </article> <article> <h1>Mapping Early Type 1 Diabetes Progression</h1> <p>Wed, 01 Jul 2026 22:00:00 GMT</p> <p>A study from the DQBM Bodenmiller Lab maps cellular and immune changes in human pancreata across the progression of type 1 diabetes.</p> </article> <article> <h1>Mapping Advanced Head and Neck Cancer</h1> <p>Tue, 30 Jun 2026 22:00:00 GMT</p> <p>An international study involving the DQBM Bodenmiller Lab reveals how treatment history and tumour characteristics shape recurrent and metastatic head and neck cancer.</p> </article> <article> <h1>Heart Volume Ratio Improves Stroke Risk Assessment</h1> <p>Sun, 17 May 2026 22:00:00 GMT</p> <p>A study involving the DQBM Menze Lab identifies the ratio between left atrial and ventricular volume as a promising marker of atrial cardiopathy and stroke risk.</p> </article> <article> <h1>Gene Therapy Reduces Spinal Injury Spasticity</h1> <p>Wed, 03 Jun 2026 22:00:00 GMT</p> <p>A study involving the DQBM Polymenidou Lab demonstrates a targeted gene therapy that reduced muscle spasticity after spinal cord injury and showed encouraging long-term safety in animal models.</p> </article> <article> <h1>Review Maps AI Advances in Chest Radiography</h1> <p>Mon, 01 Jun 2026 22:00:00 GMT</p> <p>A new review co-authored by researchers from the DQBM Krauthammer Lab surveys the evolution of AI for chest radiography, from conventional machine learning to multimodal and large language models. It highlights recent progress alongside challenges in generalisation, bias and explainability.</p> </article> <article> <h1>Machine Learning Predicts Antifungal Resistance Earlier</h1> <p>Mon, 01 Jun 2026 22:00:00 GMT</p> <p>A study involving the DQBM Krauthammer Lab combines routine mass spectrometry data with machine learning to predict antifungal resistance. The approach could provide earlier resistance warnings while conventional susceptibility testing is still underway.</p> </article> <article> <h1>Tregs Protect and Repair Infected Tissues</h1> <p>Sun, 31 May 2026 22:00:00 GMT</p> <p>A review from the DQBM Joller Lab examines how regulatory T cells balance immune suppression, pathogen control and tissue repair during infection.</p> </article> <article> <h1>Immune Architecture Predicts Melanoma Treatment Response</h1> <p>Wed, 27 May 2026 22:00:00 GMT</p> <p>A study from the DQBM Bodenmiller Lab shows that the spatial organization of immune cells in melanoma brain metastases can help predict immunotherapy response and survival.</p> </article> <article> <h1>Making Medical Imaging Data FAIR</h1> <p>Wed, 20 May 2026 22:00:00 GMT</p> <p>Researchers involving the DQBM Menze Lab developed a semantic framework that supports standardized, interoperable and reusable medical imaging metadata across Swiss health research.</p> </article> <article> <h1>Cell Death Activates Phagocytic Microglia</h1> <p>Mon, 11 May 2026 22:00:00 GMT</p> <p>A study involving the DQBM Polymenidou Lab identifies a microglial state that responds to dying cells and supports debris clearance in neurodegeneration.</p> </article> <article> <h1>BraTS-Africa Advances Inclusive Medical AI</h1> <p>Mon, 04 May 2026 22:00:00 GMT</p> <p>A study involving the DQBM Menze Lab reports progress from the BraTS-Africa Challenge, which develops and evaluates brain tumour segmentation methods using MRI data from Sub-Saharan Africa.</p> </article> <article> <h1>How Bacteria Manage Essential Metals</h1> <p>Mon, 04 May 2026 22:00:00 GMT</p> <p>A primer from the DQBM Kümmerli Lab explains how bacterial metallophores regulate metal uptake, prevent toxicity and shape interactions within microbial communities and with hosts.</p> </article> <article> <h1>Open Stroke Dataset Advances Medical AI</h1> <p>Tue, 21 Apr 2026 22:00:00 GMT</p> <p>A multicentre project involving the DQBM Menze Lab releases a longitudinal imaging dataset designed to support AI models for stroke lesion analysis and outcome prediction.</p> </article> <article> <h1>Roadmap for Clinical Bioinformatics Implementation</h1> <p>Sun, 01 Mar 2026 23:00:00 GMT</p> <p>A position article involving the DQBM Krauthammer Lab identifies major barriers preventing bioinformatics tools from moving efficiently into clinical practice.</p> </article> <article> <h1>Generalist AI for 3D CT</h1> <p>Sun, 22 Feb 2026 23:00:00 GMT</p> <p>Researchers from the Menze Lab introduce CT-RATE, the first large-scale open dataset pairing 3D chest CT scans with radiology reports. Building on this resource, they develop CT-CLIP and CT-CHAT, foundation models that advance multimodal AI for 3D medical imaging.</p> </article> <article> <h1>Hepatoblasts Shape Fetal Blood Formation</h1> <p>Sun, 15 Feb 2026 23:00:00 GMT</p> <p>Researchers reveal how hepatoblasts orchestrate hematopoietic stem cell expansion in the fetal liver. Tissue-scale mapping identifies KIT ligand as a key driver of stem cell maintenance and erythropoiesis.</p> </article> <article> <h1>AI Accelerates Pediatric Brain Tumor Segmentation</h1> <p>Thu, 12 Feb 2026 23:00:00 GMT</p> <p>A study involving the DQBM Menze Lab presents a deep learning framework that segments diverse pediatric brain tumors with accuracy comparable to human experts.</p> </article> <article> <h1>GlioMODA Streamlines Automated Glioma Segmentation</h1> <p>Wed, 11 Feb 2026 23:00:00 GMT</p> <p>Researchers involving the DQBM Menze Lab developed GlioMODA, an open-source deep learning framework for reliable glioma segmentation across incomplete and heterogeneous MRI protocols.</p> </article> <article> <h1>Mapping Cas9 PAM Diversity at Scale</h1> <p>Sat, 07 Feb 2026 23:00:00 GMT</p> <p>Researchers from the Krauthammer Lab co-developed CRISPR-PAMdb and CICERO, combining metagenomic mining and machine learning to map and predict PAM specificities across thousands of Cas9 enzymes. The study expands the genome editing target space and provides a publicly accessible resource for Cas9 selection and engineering.</p> </article> <article> <h1>Targeting DPRs Rescues ALS and FTD Phenotypes</h1> <p>Thu, 05 Feb 2026 23:00:00 GMT</p> <p>Researchers from the Polymenidou Lab demonstrate that blocking RAN translation - without altering repeat RNAs - rescues behavioral and cellular phenotypes in C9ORF72-related ALS and FTD models. The study identifies dipeptide repeat proteins as primary drivers of disease pathology.</p> </article> <article> <h1>DQBM Contributes to NCCR Children and Cancer</h1> <p>Thu, 29 Jan 2026 23:00:00 GMT</p> <p>The new NCCR Children and Cancer strengthens pediatric oncology research across Switzerland. DQBM researchers contribute expertise in biomedical data analysis and AI for clinical decision making.</p> </article> <article> <h1>PARASIDE Enables Automated MRI Sinus Analysis</h1> <p>Thu, 29 Jan 2026 23:00:00 GMT</p> <p>Researchers from the Menze Lab contributed to PARASIDE, the first fully automated T1-weighted MRI tool for whole paranasal sinus segmentation and disease scoring. The system enables objective, radiation-free assessment of chronic rhinosinusitis severity.</p> </article> <article> <h1>New BraTS-MEN-RT Dataset Published</h1> <p>Mon, 26 Jan 2026 23:00:00 GMT</p> <p>Researchers from the Menze Lab contributed to the largest multi-institutional dataset of radiotherapy planning MRIs for meningioma segmentation. The open-access resource supports the development of clinically robust AI tools for radiotherapy workflows.</p> </article> <article> <h1>Persistent T Cell Dysregulation After SARS-CoV-2 Infection</h1> <p>Mon, 19 Jan 2026 23:00:00 GMT</p> <p>A study from the Boyman Lab shows that homeostatic cytokine receptor dysregulation persists for up to one year after acute SARS-CoV-2 infection. The findings reveal prolonged T cell activation beyond virus-specific responses, highlighting sustained immune imbalance even after clinical recovery.</p> </article> <article> <h1>Robust Fetal Brain MRI Segmentation Across Pathologies</h1> <p>Thu, 15 Jan 2026 23:00:00 GMT</p> <p>A new NeuroImage study presents a data-driven strategy that improves automated fetal brain MRI segmentation, particularly in severe pathological cases.</p> </article> <article> <h1>Antibiotic Resistance Patterns Mapped in Ghana</h1> <p>Mon, 05 Jan 2026 23:00:00 GMT</p> <p>Nicole Joller and co author Anna Estrada Brull trace how regulatory T cells moved from controversial concept to Nobel Prize winning discovery and outline how this knowledge drives new therapies for autoimmunity and cancer.</p> </article> <article> <h1>Microbial Siderophores Expand Plant Iron Uptake</h1> <p>Sun, 04 Jan 2026 23:00:00 GMT</p> <p>A new <em data-end="128" data-start="113">Nature Plants</em> Perspective co-authored by DQBM proposes a revised framework for plant iron nutrition that integrates microbial siderophores as a central component.</p> </article> <article> <h1>Uncertainty-Aware Speech Analysis in Psychosis</h1> <p>Sun, 04 Jan 2026 23:00:00 GMT</p> <p>Researchers at DQBM present a multimodal model that improves speech-based assessment across the psychosis spectrum by explicitly modeling uncertainty.</p> </article> <article> <h1>Review celebrates Nobel Treg cell breakthroughs</h1> <p>Tue, 09 Dec 2025 23:00:00 GMT</p> <p>Nicole Joller and co author Anna Estrada Brull trace how regulatory T cells moved from controversial concept to Nobel Prize winning discovery and outline how this knowledge drives new therapies for autoimmunity and cancer.</p> </article> <article> <h1>Metabolomics sharpens forensic body fluid ID</h1> <p>Sun, 07 Dec 2025 23:00:00 GMT</p> <p>A new pilot study co authored by the Kümmerli Lab shows that untargeted metabolomics can distinguish nine different body fluids and tissues using LC QTOF MS. The work identifies candidate metabolite markers that could form the basis of future confirmatory forensic tests.</p> </article> <article> <h1>DQBM celebrates Christmas at Ziegelhütte</h1> <p>Thu, 04 Dec 2025 23:00:00 GMT</p> <p>The DQBM community wrapped up the year with an outdoor Christmas party at Ziegelhütte, starting with fondue and Glühwein and ending with music and a friendly Kegeln competition.</p> </article> <article> <h1>CISI Method Doubles IMC Multiplexing Power</h1> <p>Wed, 26 Nov 2025 23:00:00 GMT</p> <p>DQBM researchers, together with partners at University Hospital Zurich, ZHAW and ETH Zurich, report a participatory study co-designing OncoSupport+, a patient centered app for supportive cancer care. The work highlights digital screening, personalized information, and usability factors for adoption.</p> </article> <article> <h1>Krauthammer Lab co-designs OncoSupport+ for supportive cancer care</h1> <p>Mon, 10 Nov 2025 23:00:00 GMT</p> <p>DQBM researchers, together with partners at University Hospital Zurich, ZHAW and ETH Zurich, report a participatory study co-designing OncoSupport+, a patient centered app for supportive cancer care. The work highlights digital screening, personalized information, and usability factors for adoption.</p> </article> <article> <h1>High resolution IMC maps subcellular structures</h1> <p>Tue, 04 Nov 2025 23:00:00 GMT</p> <p>A <em data-end="508" data-start="492">Nature Methods</em> study led by DQBM’s Bodenmiller Lab introduces high resolution imaging mass cytometry that resolves submicrometer features and improves cell segmentation, extending IMC into the subcellular regime.</p> </article> <article> <h1>Benchmarking preprocessing for cfDNA fragmentomics</h1> <p>Sun, 02 Nov 2025 23:00:00 GMT</p> <p>DQBM’s Krauthammer Lab and collaborators benchmark how bioinformatics preprocessing affects cell free DNA fragment analysis, finding most features robust and offering practical recommendations for cancer detection studies.</p> </article> <article> <h1>TDP 43 PET tracers show selective, high affinity binding</h1> <p>Sun, 26 Oct 2025 23:00:00 GMT</p> <p>Nature Communications reports two fluorine 18 PET ligands that bind aggregated TDP 43 with high affinity and selectivity over Aβ, Tau, and α synuclein. ACI 19626 is prioritized for first in human evaluation.</p> </article> <article> <h1>DQBM PhD Candidate Ibrahim Hamamci Awarded 2025 Google PhD Fellowship</h1> <p>Thu, 23 Oct 2025 22:00:00 GMT</p> <p>We congratulate our PhD candidate Ibrahim Ethem Hamamci from the Department of Quantitative Biomedicine (DQBM) at the University of Zurich on receiving the prestigious 2025 Google PhD Fellowship. This award recognises his exceptional and innovative work in machine learning for medical imaging.</p> </article> <article> <h1>TIGIT promotes tissue repair in T cells</h1> <p>Thu, 16 Oct 2025 22:00:00 GMT</p> <p>The Joller Lab reveals a novel role for the co-inhibitory receptor TIGIT in driving tissue-protective functions in Treg cells following viral infection.</p> </article> <article> <h1>DQBM Engaged in Swiss-Japanese Dialogue on AI and Society</h1> <p>Sun, 05 Oct 2025 22:00:00 GMT</p> <p>Michael Krauthammer, head of the DQBM, participated in a UZH-led exchange with Japanese partners, addressing the societal impact of AI in fields such as medicine and law. The initiative aims to strengthen international academic collaboration.</p> </article> <article> <h1>Machine Learning Improves Nurse Workload Prediction</h1> <p>Sun, 21 Sep 2025 22:00:00 GMT</p> <p>Researchers from the Krauthammer Lab developed a machine learning model that predicts nursing workload with 25% greater accuracy than traditional methods. The study, conducted with the University Hospital Zurich, was published in <em data-end="427" data-start="421">JMIR</em>.</p> </article> <article> <h1>Scalable Imaging Workflows Advance Cancer Tissue Profiling</h1> <p>Sun, 14 Sep 2025 22:00:00 GMT</p> <p>A new Cell Reports Methods study co-led by the Bodenmiller Lab presents robust, large-scale workflows for imaging mass cytometry and immunofluorescence, enabling immune profiling of thousands of cancer tissues across Europe.</p> </article> <article> <h1>CD4 T cells gain innate function after activation</h1> <p>Mon, 08 Sep 2025 22:00:00 GMT</p> <p>A new study from the Joller Lab reveals that classical T cell activation equips CD4 T cells with an innate-like ability to produce IFN-γ in response to cytokines alone. The findings suggest a broader role for these cells across infections and autoimmunity.</p> </article> <article> <h1>Junior Scientist Symposium 2.0: Path to Diverse Career Paths</h1> <p>Thu, 04 Sep 2025 22:00:00 GMT</p> <p>A full‑day symposium organized entirely by DQBM JUSCOR empowered early‑career researchers with workshops, talks from industry professionals, and networking opportunities to explore academic and non‑academic careers.</p> </article> <article> <h1>Boyman Lab unveils real-time STAT biosensors</h1> <p>Sun, 31 Aug 2025 22:00:00 GMT</p> <p>A new study in <em data-end="249" data-start="224">Nature Chemical Biology</em> introduces STATeLights, biosensors developed by the Boyman Lab to monitor STAT activation in living cells.</p> </article> <article> <h1>Krauthammer Lab maps SSc disease subtypes</h1> <p>Sun, 31 Aug 2025 22:00:00 GMT</p> <p>A semi-supervised deep model trained on EUSTAR registry trajectories reveals five hierarchical systemic sclerosis subtypes across eight organs.</p> </article> <article> <h1>DQBM contributes to CROWN challenge study</h1> <p>Thu, 28 Aug 2025 22:00:00 GMT</p> <p>A new publication in <em data-end="233" data-start="209">Medical Image Analysis</em> presents results from the CROWN challenge, benchmarking automated techniques for Circle of Willis artery classification and quantification. The study involved contributions from the Menze Lab at DQBM.</p> </article> </main></body></html>